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Image Search Results
Journal: Journal of Nanobiotechnology
Article Title: Revolutionizing lymph node metastasis imaging: the role of drug delivery systems and future perspectives
doi: 10.1186/s12951-024-02408-5
Figure Lengend Snippet: The chronological progression—past, present, and anticipated future—of lymph node (LN) imaging via the medium of drug delivery systems (DDSs). Created with BioRender.com
Article Snippet:
Techniques: Imaging
Journal: Journal of Nanobiotechnology
Article Title: Revolutionizing lymph node metastasis imaging: the role of drug delivery systems and future perspectives
doi: 10.1186/s12951-024-02408-5
Figure Lengend Snippet: A brief historical overview of lymph node metastasis imaging based on DDSs. DDS drug delivery system, CT computed tomography, LSG lymphoscintigraphy, NP nanoparticle, MRI magnetic resonance imaging, ICG indocyanine green, SLN sentinel lymph node
Article Snippet:
Techniques: Imaging, Computed Tomography, Magnetic Resonance Imaging
Journal: Journal of Nanobiotechnology
Article Title: Revolutionizing lymph node metastasis imaging: the role of drug delivery systems and future perspectives
doi: 10.1186/s12951-024-02408-5
Figure Lengend Snippet: The targeted lymph node mechanisms of drug delivery systems (DDSs). A By modifying their surface charge, composition, and shape, DDSs possess the capability to elude phagocytosis activity by macrophages. B Benefitting from the EPR effect, DDSs can maintain a persistent presence within metastatic lymph nodes. C Leveraging the use of ligand-coupled NPs, DDSs have the potential to actively home in on targeted lymph nodes. D DDSs, when tailored to a specific size, gain the ability to infiltrate lymphatic vessels in substantial volumes. Created with BioRender.com
Article Snippet:
Techniques: Activity Assay
Journal: Journal of Nanobiotechnology
Article Title: Revolutionizing lymph node metastasis imaging: the role of drug delivery systems and future perspectives
doi: 10.1186/s12951-024-02408-5
Figure Lengend Snippet: The dual role of drug delivery systems (DDSs) in diagnosis and treatment, demonstrating the application of DDSs in delivering photothermal agents. These agents convert light energy into photoacoustic signals for imaging, while simultaneously releasing thermal energy, derived from light absorption, to annihilate tumor cells. Created with BioRender.com
Article Snippet:
Techniques: Biomarker Discovery, Imaging, Derivative Assay
Journal: Journal of Nanobiotechnology
Article Title: Revolutionizing lymph node metastasis imaging: the role of drug delivery systems and future perspectives
doi: 10.1186/s12951-024-02408-5
Figure Lengend Snippet: The potential risks associated with drug delivery systems (DDSs) in the context of lymph node metastasis imaging. Nanoparticle (NP)-based DDSs are not devoid of safety concerns. For instance, DDSs containing Gd may precipitate gadolinium deposition disease, causing symptoms such as fatigue and brain fog. Quantum dot-based DDSs may induce the production of reactive oxygen species (ROS) via the release of metal ions, such as the Cd ion, resulting in epigenetic modifications. Despite its initial status as an ideal, safe coating to mitigate DDS side effects, polyethylene glycol (PEG) might still instigate hypersensitivity reactions. Created with BioRender.com
Article Snippet:
Techniques: Imaging